Siemens has signed a Memorandum of Understanding with the Energy Department to support the Genesis Mission, a federal initiative to modernize America’s scientific infrastructure through advanced AI, computing and interoperable digital systems.
The Genesis Mission aims to accelerate discovery, strengthen lab-to-industry translation and reinforce U.S. technological leadership across critical domains. Siemens brings expertise in digital engineering, high-fidelity simulation, industrial AI, scientific data lifecycle management and mission-critical infrastructure.

John Ustica, president and CEO at Siemens Government Technologies, said in a LinkedIn post:
“Joining in the Genesis Mission is a great privilege for our team at SGT. By combining industrial AI capabilities from Siemens with our extensive experience supporting the national labs, we look forward to supporting the U.S. Department of Energy (DOE) in this generational endeavor to ensure American scientific leadership now and in the decades to come.”
Rather than delivering isolated AI models or point solutions, Siemens integrates AI directly into engineering, validation and operational workflows — uniting scientific data, physics-informed simulation, digital twins, automation systems and secure infrastructure into a single connected stack. That continuity from research to deployment is designed to help translate breakthrough research into reliable, real-world impact across energy, manufacturing and infrastructure.
Through the MOU, Siemens will work with DOE, interagency stakeholders and private sector partners on interoperable digital infrastructure for science and engineering, including AI-enabled simulation, digital twins, scientific data lifecycle governance and lab-to-deployment workflows.
“The Genesis Mission’s goal of accelerating scientific discovery and scaling it in the real world is a perfect match for our core expertise: combining the real and the digital worlds,” said Roland Busch, president and CEO of Siemens AG. “Our leadership in industrial AI and advanced simulation is proven in national laboratories and industrial ecosystems across the United States and worldwide. We look forward to contributing these capabilities to make the Genesis Mission a success.”